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An Investigation into the Factors that Contribute to Women Leaving Scientific Roles for Support Roles
(2021-05-21)
Diverse perspectives and ideas are crucial for driving innovation. However, Science,
Technology, Engineering, and Mathematics (STEM) occupations do not represent the
diversity seen in the US population and are therefore ...
Assessment of a Resource and Descriptive Analysis of Participants with Multiple Primary Cancers
(2023-04-28)
We conducted an analysis of participants in the Nurses’ Health Study (NHS) and Nurses’ Health Study II (NHSII) cohorts, longitudinal studies with 34-47 years of follow-up, conducted jointly by Brigham and Women’s Hospital ...
Investigating the Role of The Antioxidant N-acetylcarnosine in Attenuating Oxidation-induced Retinal Damage in Retinitis Pigmentosa
(2021-09-14)
The goal of this research was to explore the strong antioxidant, n-acetylcarnosine, in its capacity to ameliorate oxidative stress, specifically in the context of slowing disease progression of retinal degeneration. Retinal ...
Identifying Novel Modifiable Risk Factors in Progressive Supranuclear Palsy (PSP): A Secondary Use Analysis of Clinical Trial Data
(2023-10-05)
Much of the current research efforts to treat neurological diseases have been focused on identifying novel disease biomarkers to aid in diagnosis, provide prognostic information, and monitor disease progression. Yet none ...
Identification of a Robust Antibody Modulator of CD33 in In Vitro Models
(2023-09-14)
CD33 is a sialic acid binding immunoglobulin-type lectin found on myeloid cells throughout the body, including microglia, the brain’s resident immune cells. CD33 has been implicated genetically in late-onset Alzheimer’s ...
Whole Genome Investigation of Genomic Aberrations of Rare Genetic Conditions Using Joint Analysis
(2023-10-11)
Genomic analysis is a method designed to assign meaning to the nucleotides of
DNA and translate them into readable information. The decreasing cost and increasing
efficiency of genomic sequencing have enabled the integration ...
Revealing Ancestral Arachnid Genes by Tracking Acetylcholinesterase Evolution in Spiders
(2023-10-19)
Acetylcholinesterase (AChE) is a vital enzyme which plays a key role in
regulation of neurotransmission in spiders and other animals. Because it is of critical
importance, this protein is targeted by many toxins, including ...
Recombinant Protein Production using a Mammalian Unconventional Secretory Pathway
(2023-10-19)
Recombinant proteins are widely used throughout biomedical research, and the expansive and diversified usage of such reagents requires continued development of novel production processes. Unconventional protein secretion ...
Factors of Climate Change and Their Influence on Lyme Disease Infection Rates
(2023-12-15)
Lyme disease is carried solely by the Blacklegged Tick, or Ixodes scapularis,
which transmit it from host animal to host animal. I. scapularis causes most Lyme
disease infections as they are the best at feeding on animals ...
Comparative Assessment of SARS-CoV-2 Diagnostics in Nigeria
(2024-01-16)
Viral pandemics are a major threat to public health, as they have the potential to overwhelm health systems and cause a significant loss of lives and economic meltdown. The COVID-19 pandemic highlighted not only the impact ...