Browsing by Author "Bosch, Ronald"
Now showing items 21-26 of 26
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Safety and immunogenicity of therapeutic DNA vaccination in individuals treated with antiretroviral therapy during acute/early HIV-1 infection
Graham, Barney S.; Stocker, Vicki; Maenza, Janine; Markowitz, Martin; Little, Susan; Collier, Ann C.; Nabel, Gary; Saindon, Suzanne; Flynn, Theresa; Ostrowski, Mario A.; Rosenberg, Eric Scott; Chan, Ellen S.L.; Bosch, Ronald J.; Sax, Paul Edward; Kuritzkes, Daniel Robert; Barouch, Dan Hung (Public Library of Science, 2010)Background: An effective therapeutic vaccine that could augment immune control of HIV-1 replication may abrogate or delay the need for antiretroviral therapy. AIDS Clinical Trials Group (ACTG) A5187 was a phase I/II, ... -
Sex differences in the effects of maternal vitamin supplements on mortality and morbidity among children born to HIV-infected women in Tanzania
Kawai, Kosuke; Msamanga, Gernard; Manji, Karim; Villamor, Eduardo; Bosch, Ronald J.; Hertzmark, Ellen; Fawzi, Wafaie W. (Cambridge University Press (CUP), 2010)We examined whether there are sex differences in the effect of vitamin supplements on birth outcomes, mortality, and morbidity by two years of age among children born to HIV-infected women in Tanzania. A randomized ... -
TLR7/9 Antagonist Reduces HIV-1-Induced Immune Activation
Chang, Ju-Hui; Lindsay, RJ; Doyle, EH; Vrbanac, Vladimir; Seung, Edward N.; Dudek, Timothy E; Bosch, Ronald J.; Precopio, M; Kandimalla, E; Tager, Andrew Martin; Altfeld, Marcus (BioMed Central, 2012) -
Transcriptional Changes in CD8+ T Cells During Antiretroviral Therapy Intensified With Raltegravir
Ouyang, Zhengyu; Buzon, Maria J.; Zheng, Lu; Sun, Hong; Yu, Xu G.; Bosch, Ronald J.; Mellors, John W.; Eron, Joseph J.; Gandhi, Rajesh T.; Lichterfeld, Mathias (Oxford University Press, 2015)Background. Intensification of antiretroviral therapy with raltegravir does not affect levels of residual human immunodeficiency virus (HIV)-1 viremia, but it has led to increased levels of episomal HIV-1 DNA in some ... -
A Trial of the Effect of Micronutrient Supplementation on Treatment Outcome, T Cell Counts, Morbidity, and Mortality in Adults with Pulmonary Tuberculosis
Villamor, Eduardo; Mugusi, Ferdinand; Urassa, Willy; Bosch, Ronald J.; Saathoff, Elmar; Matsumoto, Kenji; Meydani, Simin N.; Fawzi, Wafaie W. (Oxford University Press (OUP), 2008)Background Tuberculosis (TB) often coincides with nutritional deficiencies. The effects of micronutrient supplementation on TB treatment outcomes, clinical complications, and mortality are uncertain. Methods We ... -
Vitamin D status and TB treatment outcomes in adult patients in Tanzania: a cohort study
Mehta, Saurabh; Mugusi, Ferdinand M; Bosch, Ronald J; Aboud, Said; Urassa, Willy; Villamor, Eduardo; Fawzi, Wafaie W (BMJ Publishing Group, 2013)Objectives: Vitamin D is an immunomodulator and can alter response to tuberculosis (TB) treatment, though randomised trials have been inconclusive to date. We present one of the first comprehensive analysis of the associations ...