Multicenter comparison of laboratory performance in cytomegalovirus and Epstein-Barr virus viral load testing using international standards
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Author
Rychert, Jenna
Danziger-Isakov, Lara
Yen-Lieberman, Belinda
Storch, Gregory
Buller, Richard
Sweet, Stewart C.
Mehta, Aneesh K.
Cheeseman, Jennifer A.
Heeger, Peter
Published Version
https://doi.org/10.1111/ctr.12473Metadata
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Rychert, Jenna, Lara Danziger-Isakov, Belinda Yen-Lieberman, Gregory Storch, Richard Buller, Stewart C. Sweet, Aneesh K. Mehta, et al. 2014. “Multicenter Comparison of Laboratory Performance in Cytomegalovirus and Epstein-Barr Virus Viral Load Testing Using International Standards.” Clinical Transplantation 28 (12) (November 13): 1416–1423. doi:10.1111/ctr.12473.Abstract
Background—Infections with cytomegalovirus (CMV) and Epstein Barr Virus (EBV) remain important in solid organ transplantation. Quantitative viral nucleic acid testing is a major advance to patient management. These assays are limited by a lack of standardization, resulting in viral load measurements that differ among clinical laboratories. The variability in viral load measurements makes interpretation of multicenter clinical trials data difficult. This study compares the current practices in CMV and EBV viral load testing at four large transplant centers participating in multicenter Clinical Trials in Organ Transplantation (CTOT/CTOTC).Other Sources
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481866/Terms of Use
This article is made available under the terms and conditions applicable to Open Access Policy Articles, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#OAPCitable link to this page
https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37364478
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