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dc.contributor.authorBrauer, Carmen A.
dc.contributor.authorCutler, David M.
dc.contributor.authorCoca-Perraillon, Marcelo
dc.date.accessioned2017-04-24T16:07:26Z
dc.date.issued2009
dc.identifier.citationBrauer, Carmen A., David M. Cutler, Marcelo Coca-Perraillon, Allison B. Rosen. 2009. “Incidence and Mortality of Hip Fractures in the United States.” JAMA 302 (14) (October 14): 1573. doi:10.1001/jama.2009.1462.en_US
dc.identifier.issn0098-7484en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:32306636
dc.description.abstractContext: Understanding the incidence and subsequent mortality following hip fracture is essential to measuring population health and the value of improvements in health care. Objective: To examine trends in hip fracture incidence and resulting mortality over 20 years in the US Medicare population. Design, Setting, and Patients: Observational study using data from a 20% sample of Medicare claims from 1985-2005. In patients 65 years or older, we identified 786 717 hip fractures for analysis. Medication data were obtained from 109 805 respondents to the Medicare Current Beneficiary Survey between 1992 and 2005. Main Outcome Measures: Age- and sex-specific incidence of hip fracture and age- and risk-adjusted mortality rates. Results: Between 1986 and 2005, the annual mean number of hip fractures was 957.3 per 100 000 (95% confidence interval [CI], 921.7-992.9) for women and 414.4 per 100 000 (95% CI, 401.6-427.3) for men. The age-adjusted incidence of hip fracture increased from 1986 to 1995 and then steadily declined from 1995 to 2005. In women, incidence increased 9.0%, from 964.2 per 100 000 (95% CI, 958.3-970.1) in 1986 to 1050.9 (95% CI, 1045.2-1056.7) in 1995, with a subsequent decline of 24.5% to 793.5 (95% CI, 788.7-798.3) in 2005. In men, the increase in incidence from 1986 to 1995 was 16.4%, from 392.4 (95% CI, 387.8-397.0) to 456.6 (95% CI, 452.0-461.3), and the subsequent decrease to 2005 was 19.2%, to 369.0 (95% CI, 365.1-372.8). Age- and risk-adjusted mortality in women declined by 11.9%, 14.9%, and 8.8% for 30-, 180-, and 360-day mortality, respectively. For men, age- and risk-adjusted mortality decreased by 21.8%, 25.4%, and 20.0% for 30-, 180-, and 360-day mortality, respectively. Over time, patients with hip fracture have had an increase in all comorbidities recorded except paralysis. The incidence decrease is coincident with increased use of bisphosphonates. Conclusion: In the United States, hip fracture rates and subsequent mortality among persons 65 years and older are declining, and comorbidities among patients with hip fractures have increased. The number of hip fractures occurring in the United States and the resulting postsurgical outcome are a major public health concern. About 30% of people with a hip fracture will die in the following year,1- 3 and many more will experience significant functional loss.4- 7 The long-term consequences may be great as well. Some studies have shown excess long-term mortality even 10 years after an episode,8- 12 although other studies have only shown moderate increases in mortality.13- 17. Treating hip fractures is also very expensive. A typical patient with a hip fracture spends US $40 000 in the first year following hip fracture for direct medical costs and almost $5000 in subsequent years.1,18- 20 Despite recent literature indicating that the hip fracture incidence may be stabilizing or decreasing,21- 29 concern still exists that because of the aging of the population, the hip fracture incidence will increase worldwide unless additional steps are taken.7,19,20,22,30- 35. Understanding the incidence and postsurgical outcome of hip fractures is a vital first step in improving population health. Our primary objective was to assess trends in the age- and sex-specific incidence and subsequent age- and risk-adjusted mortality of hip fractures among elderly individuals in the United States, controlling for comorbid conditions. A secondary objective was to examine trends in pharmaceutical use because this may affect fracture incidence, mortality, or both.en_US
dc.language.isoen_USen_US
dc.publisherAmerican Medical Association (AMA)en_US
dc.relation.isversionofdoi:10.1001/jama.2009.1462en_US
dc.relation.hasversionhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410861/en_US
dash.licenseLAA
dc.titleIncidence and Mortality of Hip Fractures in the United Statesen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalJAMAen_US
dash.depositing.authorCutler, David M.
dc.date.available2017-04-24T16:07:26Z
dc.identifier.doi10.1001/jama.2009.1462*
dash.contributor.affiliatedCutler, David


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