Are we there yet? Tracking the Development of New Model Systems
View/ Open
Publisher pdf--must be dark. (773.6Kb)
Access Status
Full text of the requested work is not available in DASH at this time ("restricted access"). For more information on restricted deposits, see our FAQ.Author
Groover, Andrew
Hodges, Scott A.
Monteiro, Antonia
Published Version
https://doi.org/10.1016/j.tig.2008.04.002Metadata
Show full item recordCitation
Abzhanov, Arhat, Cassandra G. Extavour, Andrew Groover, Scott A. Hodges, Hopi E. Hoekstra, Elena M. Kramer, and Antonia Monteiro. 2008. Are we there yet? Tracking the development of new model systems. Trends in Genetics 24(7): 353-360.Abstract
It is increasingly clear that additional "model" systems are needed to elucidate the genetic and developmental basis of organismal diversity. Whereas model system development previously required enormous investment, recent advances including the decreasing cost of DNA sequencing and the power of reverse genetics to study gene function are greatly facilitating the process. In this review, we consider two aspects of the development of new genetic model systems: first, the types of questions being advanced using these new models; and second, the essential characteristics and molecular tools for new models, depending on the research focus. We hope that researchers will be inspired to explore this array of emerging models and even consider developing new molecular tools for their own favorite organism.Citable link to this page
http://nrs.harvard.edu/urn-3:HUL.InstRepos:2925274
Collections
- FAS Scholarly Articles [18304]
Contact administrator regarding this item (to report mistakes or request changes)