dc.contributor.author | Bogoch, Isaac I. | en_US |
dc.contributor.author | Wilson, Michael R. | en_US |
dc.contributor.author | Chad, David A. | en_US |
dc.contributor.author | Venna, Nagagopal | en_US |
dc.date.accessioned | 2015-06-02T12:21:57Z | |
dc.date.issued | 2015 | en_US |
dc.identifier.citation | Bogoch, Isaac I., Michael R. Wilson, David A. Chad, and Nagagopal Venna. 2015. “Acute lower motor neuron syndrome and spinal cord gray matter hyperintensities in HIV infection.” Neurology® Neuroimmunology & Neuroinflammation 2 (4): e113. doi:10.1212/NXI.0000000000000113. http://dx.doi.org/10.1212/NXI.0000000000000113. | en |
dc.identifier.issn | 2332-7812 | en |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:16120977 | |
dc.description.abstract | Objective: To describe a novel manifestation of lower motor neuron disease in patients with well-controlled HIV infection. Methods: A retrospective study was performed to identify HIV-positive individuals with acute, painful lower motor neuron diseases. Results: Six patients were identified with HIV and lower motor neuron disease. Two patients met the inclusion criteria of well-controlled, chronic HIV infection and an acute, painful, unilateral lower motor neuron paralytic syndrome affecting the distal portion of the upper limb. These patients had segmental T2-hyperintense lesions in the central gray matter of the cervical spinal cord on MRI. One patient stabilized and the second patient improved with immunomodulatory therapy. Conclusions: This newly described syndrome expands the clinical spectrum of lower motor neuron diseases in HIV. | en |
dc.language.iso | en_US | en |
dc.publisher | Lippincott Williams & Wilkins | en |
dc.relation.isversionof | doi:10.1212/NXI.0000000000000113 | en |
dc.relation.hasversion | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436596/pdf/ | en |
dash.license | LAA | en_US |
dc.title | Acute lower motor neuron syndrome and spinal cord gray matter hyperintensities in HIV infection | en |
dc.type | Journal Article | en_US |
dc.description.version | Version of Record | en |
dc.relation.journal | Neurology® Neuroimmunology & Neuroinflammation | en |
dash.depositing.author | Wilson, Michael R. | en_US |
dc.date.available | 2015-06-02T12:21:57Z | |
dc.identifier.doi | 10.1212/NXI.0000000000000113 | * |
dash.contributor.affiliated | Chad, David A. | |
dash.contributor.affiliated | Venna, Nagagopal | |
dash.contributor.affiliated | Wilson, Michael | |