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Noninvasive Translational Approaches to Study the Disease Pathogenesis of Patients with Atopic Dermatitis
(2021-08-20)
Atopic dermatitis (AD) is a chronic or acute inflammatory skin condition that affects many children and adults and can be severe and debilitating. It is characterized by itchy, dry, red, flaky skin and it is caused by ...
The Fourth Intracellular Src Homology 3 Binding Motif of CD2 is Required for Durable T Cell Activity
(2023-04-21)
Recent research from both the bench and clinic have demonstrated the importance of the CD2/CD58 axis in the effectiveness of T cells in diseases where chronic antigen exposure is common. Despite this understanding, the ...
Recommendations for Improving the Diagnostic Criteria for Mast Cell Activation Syndrome
(2024-01-02)
Mast Cell Activation Syndrome (MCAS) is a disorder in which patients experience a wide variety of frequently debilitating allergic reactions and symptoms. The onset can be sudden, and it is often a life-changing disorder ...
Spatiotemporal Reassortment of Th1 Migratory Receptors in Inflamed Skin
(2024-05-15)
CD4+ T helper (Th) cells search a vast tissue area to find sites of infection or inflammation. The distribution of Th cells in tissues is shaped by tissue architecture, chemotactic cues, adhesion molecules, and the location ...