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Using Cyclic Immunofluorescence (CyCIF), Deep-learning, and Human Tumor Microarrays (hTMAs) for Antibody Validation and Creation of an Atlas of Cancers Emphasizing Unique Phenotypes
(2023-01-10)
All cancers are different from each other, in their mutation spectrum, primary location of occurrence, and metastases as well as their phenotypic traits and tumor composition. For years, clinicians and pathologists have ...
A Novel Framework for Medical Learning: Using AI Based Grad-CAM for Improving Otitis Media Diagnosis
(2023-01-10)
Otitis Media (OM) and its sub-categories of pathology are the number one pathology in children. Diagnosis is very difficult as it requires visual inspection the tympanic membrane of a child, which is in view for only a few ...
Investigation of Microplastics from Deep-Sea Antarctic and West Coast North American Sediments
(2023-01-23)
Microplastics have been found to be widespread and pervasive across marine
ecosystems. There is growing body of literature to indicate that microplastics are globally
distributed, including in deep sea sediments, yet there ...
Bioproduction of D-Tagatose in Escherichia coli by Harnessing the Reverse Leloir Pathway
(2023-01-11)
D-Tagatose is a natural, rare monosaccharide containing 38% of the calories of sucrose. As an alternative sweetener, it offers numerous benefits including a low glycemic index, prebiotic properties, and the ability to lower ...
Identifying Non-canonical, Keap1-independent Regulators of Nrf2 Degradation in Non-small Cell Lung Cancer
(2022-12-21)
Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription factor responsible for cellular antioxidant response to oxidative and electrophilic stress. Keap1 (Kelch ECH associating protein 1) has been demonstrated ...
Ecological Factors and Jaw Morphology in Lepidosauria: A Geometric Morphometric and Biomechanical Approach
(2023-04-20)
Lepidosauria consists of two reptilian orders, with squamates, the larger of the orders, consisting of about 11,000 species and are widespread globally. As a group, lepidosaurs are very diverse in habitat, leg development, ...
Gamma Induction Using Transcranial Alternating Current Stimulation in Alzeihmer’s Disease
(2021-05-12)
Thanks to technology and advances in the medical field, our population's lifespan continues to lengthen. As a result, aging related neurodegenerative disorders become more prevalent. Manipulating brain oscillations is a ...
Lifestyle Medicine as an Effective Virtual Intervention for Stroke Survivors
(2021-05-14)
Lifestyle medicine is the use of healthy lifestyle habits such as sleep, diet, physical exercise and social connections, as a primary therapeutic modality for treatment and reversal of chronic disease. Stroke is one of the ...
Systematic Investigation into EndoRiftia Flagellar System Suggests Possibility of System Co-Option for Additional Functionality
(2021-08-20)
The overarching goal of this study is to contribute to the development of the Candidatus Endoriftia persephone-Riftia pachyptila symbiotic association as a biological model system with a more specific goal being to ...
Understanding Fat Cadherins from an Evolutionary and Contextual Point of View
(2022-01-06)
Fat cadherins are an essential planar cell polarity molecule that is conserved throughout evolution. Yet little is known about what regions of these molecules has been conserved over time. This thesis describes the importance ...