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Screening Potential Treatments of Hepatocellular Carcinoma through Single-Cell RNA Sequencing and the Connectivity Map
(2022-12-08)
Hepatocellular carcinoma (HCC) is the most common form of liver cancer, which is the second most prevalent cause of cancer mortalities worldwide. The current standard of care for non-resectable HCC is to combine immunotherapy ...
An Investigation into the Genetic and Bacterial Factors That Cause Irritable Bowel Syndrome and a Solution in the Form of a Targeted Next Generation Sequencing Compatible Gene Panel for the Disease.
(2023-05-01)
Irritable Bowel Syndrome (IBS) is a prevalent disease without complete
mechanistic understanding. Medical doctors and scientists alike do not know the cause
for the disease and therefore have trouble accurately diagnosing ...
Comparative Phylogeography of the Northern Australian Monsoon Tropics by Whole Genome Resequencing of two Species of the Avian Genus Climacteris
(2021-05-14)
Abstract
Phylogeography combines geographic information with phylogenetic analysis to gain insight into the origin, dispersal, and speciation dynamics of populations. Advances in the utility of Next Generation Sequencing ...
Purification and characterization of checkpoint blockade enhancing molecules from Coprobacillus cateniformis.
(2023-12-19)
Checkpoint blockade treatment enhancement is one of the frontline areas of study in cancer treatment, however it comes with two large drawbacks, the limited number of cancer lines in which efficacy is shown and the difficulty ...
A Framework for The Study of Compound Interactions in L1000
(2024-05-09)
Treatment combinations are used broadly in clinical settings and are used to treat a variety of diseases and disorders. Despite the potential power of combination therapies to improve the lives of more patients, the complete ...