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Gamma Induction Using Transcranial Alternating Current Stimulation in Alzeihmer’s Disease
(2021-05-12)
Thanks to technology and advances in the medical field, our population's lifespan continues to lengthen. As a result, aging related neurodegenerative disorders become more prevalent. Manipulating brain oscillations is a ...
Lifestyle Medicine as an Effective Virtual Intervention for Stroke Survivors
(2021-05-14)
Lifestyle medicine is the use of healthy lifestyle habits such as sleep, diet, physical exercise and social connections, as a primary therapeutic modality for treatment and reversal of chronic disease. Stroke is one of the ...
Systematic Investigation into EndoRiftia Flagellar System Suggests Possibility of System Co-Option for Additional Functionality
(2021-08-20)
The overarching goal of this study is to contribute to the development of the Candidatus Endoriftia persephone-Riftia pachyptila symbiotic association as a biological model system with a more specific goal being to ...
Converting Conventional Antibodies into ScFv and ScFv-Fc Fusion Fragments to Improve Expression and Function
(2021-05-06)
Antibodies are used in many diagnostic, therapeutic, and research applications around the world. Traditionally, conventional full-length antibodies have been used for these applications, however, with the development of ...
Noninvasive Translational Approaches to Study the Disease Pathogenesis of Patients with Atopic Dermatitis
(2021-08-20)
Atopic dermatitis (AD) is a chronic or acute inflammatory skin condition that affects many children and adults and can be severe and debilitating. It is characterized by itchy, dry, red, flaky skin and it is caused by ...
Synthesis of Proteolysis Targeting Chimera Components with Pedagogical Applications for the Teaching–Research Nexus
(2021-05-24)
Proteolysis targeting chimeras (PROTACs) exploit endogenous cellular ubiquitination mechanisms to selectively degrade proteins by initiating complexation between ubiquitin ligases and target substrates. Immunomodulatory ...
Plant-based diets and risk of erectile dysfunction in young men
(2021-05-14)
Erectile dysfunction (ED) is the most common medical issue associated with aging. Beyond the obvious impact on sexual quality of life, data suggests that ED may be an early indicator cardiometabolic disease. In fact, ...
Waking Experience and Circadian Rhythms Result in Differential Modulation of Sleep and Wake States
(2021-10-15)
Sleep is thought to be tightly regulated by two processes, a homeostatic and a circadian process, which interact in a complex way to integrate prior wakefulness and circadian time (Borbély et al., 1982). Despite extensive ...
Discovery of SOX10 as a Key Pharmacodynamic Marker of BRM/BRG1 Inhibition in Uveal Melanoma
(2021-05-24)
Epigenetic dysregulation plays a fundamental role in the development of cancer. Chromatin remodeling complexes are major epigenetic modifiers, and defects in its activity has emerged as an important feature causing aberrant ...
Systematic Investigation into Endoriftia Flagellar System Suggests Possibility of System Co-Option for Additional Functionality
(2021-06-15)
The overarching goal of this study is to contribute to the development of the Candidatus Endoriftia persephone-Riftia pachyptila symbiotic association as a biological model system with a more specific goal being to ...