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Impact Factors of the Nephrectomy Outcomes
(2022-05-10)
Renal cell carcinoma (RCC) represents approximately 3% of all cancers with a high incidence, especially in western countries. There has been an increasing annual trend during the last two decades. For the localized RCC ...
PATIENT SURVIVAL WITH ypT0N+ FOLLOWING NEOADJUVANT THERAPY IN GASTRIC AND RECTAL CANCERS
(2021-06-23)
Background
Survival outcomes of gastric and rectal cancer patients who developed ypT0N+ remain poorly characterized.
Methods
A survival analysis of the NCDB was conducted on patients with gastric or rectal adenocarcinoma ...
Examination of brain tumor-associated astrocytes at single-cell resolution
(2021-07-19)
Astrocytes are multifunctional cells of the central nervous system (CNS), are intimately linked into the immune modulatory processes that govern homeostasis and neuroinflammation, and display significant functional ...
Impact of Tumour Genomics on Response to standard Neo-adjuvant Chemotherapy in Triple Negative Breast Cancer, Integrative co-expression network analysis of mRNA and miRNA profile identifies miRNA 664 as an inhibitor of key genes in Triple negative breast cancer.
(2022-05-10)
Abstract - Paper 1
Background
The genomic delineation of breast cancer is a novel approach to evaluating the disease. The opportunities arising from this genomic data analysis help in identifying specific cell line ...
COMPREHENSIVE FUNCTIONAL AND MOLECULAR PROFILING AND INTEGRATIVE ANALYSES OF PRIMARY AND METASTATIC TRIPLE NEGATIVE BREAST CANCERS
(2022-05-10)
In summary, the first project was focused on investigating inter/intra-tumor epigenetic heterogeneity in TNBCs and its functional relevance. We characterized the heterogeneity of TNBCs, by combining functional and molecular ...
Validation of Clinical Prediction Models and Study of the Role of Modern Therapies Using Real-World Data in Spine Oncology
(2021-06-23)
With a rising incidence of cancer and improved life expectancy, more patients are being diagnosed and surviving longer with spinal metastases. Spinal metastases can significantly worsen patients' quality of life because ...
INHIBITING DNA MISMATCH REPAIR IN COLORECTAL CANCER
(2023-05-10)
Colorectal cancer (CRC) remains one of the most prevalent cancers in the US with a high mortality rate. Locally advanced and metastatic CRC have poor prognosis and only a small subset (5- 15%) of patient tumors with DNA ...
Engineered stem cells releasing oncolytic virus and immunomodulators have therapeutic efficacy in brain metastatic tumors
(2023-05-11)
Background: Brain metastasis is common among patients with advanced lung cancer and melanoma and is associated with significant morbidity and mortality. Conventional treatments, such as surgery, radiation, and chemotherapy, ...
Concordance between Patient-Proxy reporting of Quality of Life in Pediatric Cancer Care
(2023-05-03)
Background: Over the past three decades, health-related quality of life (HRQoL) assessment has emerged as a critical component in the clinical care of patients. Parent proxies are a crucial aspect of HRQoL assessment in ...
Smoking Status Among Cancer Patients and its Impact on Health-related Quality of Life (HRQoL): A U.S Nationwide Representative Analysis.
(2023-05-11)
By 2023, an alarming 1,958,310 new cancer cases will arise across the United States.(1) To put things into perspective, in January 2019, 16.9 million people--roughly 5% of the population--were living with cancer in the ...