Browsing by Keyword "p190RhoGAP"

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    • A Mechanosensitive Transcriptional Mechanism That Controls Angiogenesis 

      Mammoto, Akiko; Connor, Kip; Mammoto, Tadanori; Yung, Chong W.; Huh, Dongeun; Aderman, Christopher Michael; Mostoslavsky, Gustavo; Smith, Lois Elaine Hodgson; Ingber, Donald Elliott (Nature Publishing Group, 2009)
      Angiogenesis is controlled by physical interactions between cells and extracellular matrix as well as soluble angiogenic factors, such as VEGF. However, the mechanism by which mechanical signals integrate with other ...

    • MVP-Associated Filamin A Mutations Affect FlnA-PTPN12 (PTP-PEST) Interactions 

      Duval, Damien; Labbé, Pauline; Bureau, Léa; Le Tourneau, Thierry; Norris, Russell A.; Markwald, Roger R.; Levine, Robert; Schott, Jean-Jacques; Mérot, Jean (2015)
      Although the genetic basis of mitral valve prolapse (MVP) has now been clearly established, the molecular and cellular mechanisms involved in the pathological processes associated to a specific mutation often remain to be ...