Browsing by Keyword "Yeast"

Now showing items 1-7 of 7

    • Anion Exchanger 2 Regulates Dectin-1-Dependent Phagocytosis and Killing of Candida albicans 

      Urso, Katia; Charles, Julia F.; Shull, Gary E.; Aliprantis, Antonios O.; Balestrieri, Barbara (Public Library of Science, 2016)
      Anion exchanger 2 (Ae2; gene symbol, Slc4a2) is a plasma membrane Cl-/HCO3- exchanger expressed in the gastrointestinal tract, kidney and bone. We have previously shown that Ae2 is required for the function of osteoclasts, ...

    • A Model for Cell Wall Dissolution in Mating Yeast Cells: Polarized Secretion and Restricted Diffusion of Cell Wall Remodeling Enzymes Induces Local Dissolution 

      Huberman, Lori B.; Murray, Andrew W. (Public Library of Science, 2014)
      Mating of the budding yeast, Saccharomyces cerevisiae, occurs when two haploid cells of opposite mating types signal using reciprocal pheromones and receptors, grow towards each other, and fuse to form a single diploid ...

    • On epistasis and adaptation in the budding yeast Saccharomyces cerevisiae 

      Johnson, Milo (2021-08-30)
      The diverse forms of life which surround us today are the product of long lines of mutations, all running back to a common ancestor. Along these interconnected lines of evolutionary history, DNA sequences have been duplicated, ...

    • A Predictive Model for Yeast Cell Polarization in Pheromone Gradients 

      Muller, Nicolas; Piel, Matthieu; Calvez, Vincent; Voituriez, Raphaël; Gonçalves-Sá, Joana; Guo, Chin-Lin; Jiang, Xingyu; Murray, Andrew; Meunier, Nicolas (Public Library of Science, 2016)
      Budding yeast cells exist in two mating types, a and α, which use peptide pheromones to communicate with each other during mating. Mating depends on the ability of cells to polarize up pheromone gradients, but cells also ...

    • Probiotic Yeast Inhibits VEGFR Signaling and Angiogenesis in Intestinal Inflammation 

      Chen, Xinhua; Yang, Guoxun; Song, Joo-Hye; Xu, Huansheng; Li, Dan; Goldsmith, Jeffrey David; Zeng, Huiyan; Parsons-Wingerter, Patricia A.; Reinecker, Hans-Christian; Kelly, Ciaran Patrick (Public Library of Science, 2013)
      Background and Aims Saccharomyces boulardii (Sb) can protect against intestinal injury and tumor formation, but how this probiotic yeast controls protective mucosal host responses is unclear. Angiogenesis is an integral ...

    • The Role of Candida albicans SPT20 in Filamentation, Biofilm Formation and Pathogenesis 

      Tan, Xiaojiang; Fuchs, Beth Burgwyn; Wang, Yan; Chen, Weiping; J. Yuen, Grace; Chen, Rosalyn B.; Jayamani, Elamparithi; Anastassopoulou, Cleo; Pukkila-Worley, Read; Coleman, Jeffrey J.; Mylonakis, Eleftherios (Public Library of Science, 2014)
      Candida albicans is a ubiquitous fungus, which can cause very serious and sometimes life-threatening infections in susceptible patients. We used Caenorhabditis elegans as a model host to screen a library of C. albicans ...

    • Structure-Function Analysis of the Conserved Histone Chaperone Spt6 

      Loeliger, Erin Michelle (2014-06-06)
      Chromatin structure is crucial to regulate access to the genome for processes such as a transcription, recombination, DNA repair, and DNA replication. Spt6, a key factor involved in regulating chromatin structure, is ...