Browsing by Keyword "Y chromosome"
Now showing items 1-5 of 5
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Chromatin-Associated Proteins HP1 and Mod(mdg4) Modify Y-Linked Regulatory Variation in the Drosophila Testis
(Genetics Society of America, 2013)Chromatin remodeling is crucial for gene regulation. Remodeling is often mediated through chemical modifications of the DNA template, DNA-associated proteins, and RNA-mediated processes. Y-linked regulatory variation (YRV) ... -
Epigenetic Effects of Polymorphic Y Chromosomes Modulate Chromatin Components, Immune Response, and Sexual Conflict
(National Academy of Sciences, 2010)Genetic conflicts between sexes and generations provide a foundation for understanding the functional evolution of sex chromosomes and sexually dimorphic phenotypes. Y chromosomes of Drosophila contain multi-megabase ... -
Natural Variation of the Y Chromosome Suppresses Sex Ratio Distortion and Modulates Testis-Specific Gene Expression in Drosophila Simulans
(Nature Publishing Group, 2013)X-linked sex-ratio distorters that disrupt spermatogenesis can cause a deficiency in functional Y-bearing sperm and a female-biased sex ratio. Y-linked modifiers that restore a normal sex ratio might be abundant and favored ... -
Patterns of molecular evolution and epistasis on a genomic and genic scale
(2013-10-08)Epistasis describes non-additive interactions which affect gene expression and phenotype. It can happen on multiple levels, including on a genomic level with interactions between genes or even chromosomes affecting global ... -
Sex-biased chromatin and regulatory cross-talk between sex chromosomes, autosomes, and mitochondria
(BioMed Central, 2014)Several autoimmune and neurological diseases exhibit a sex bias, but discerning the causes and mechanisms of these biases has been challenging. Sex differences begin to manifest themselves in early embryonic development, ...