Browsing by Keyword "S phase"
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Polo-Like Kinase 1 Depletion Induces DNA Damage in Early S Prior to Caspase Activation
(American Society for Microbiology, 2009)Polo-like kinase 1 (Plk1) plays several roles in mitosis, and it has been suggested to have a role in tumorigenesis. We have previously reported that Plk1 depletion results in cell death in cancer cells, whereas normal ...