Browsing by Keyword "O-GlcNAc Transferase"
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Engineering a proximity-directed O-GlcNAc transferase to control O-GlcNAc signaling
(2021-11-16)O-GlcNAc is a ubiquitous monosaccharide posttranslational modification analogous to phosphorylation found on thousands of nuclear and cytoplasmic proteins involved in every major cellular process. Dysregulation of O-GlcNAc ... -
Impact of Structural Alterations on the Cellular Functions and Interactions of O-GlcNAc Transferase
(2023-06-01)O-GlcNAc Transferase (OGT) is an essential mammalian glycosyltransferase that catalyzes O-GlcNAcylation of serine and threonine residues and cleavage of Host Cell Factor 1. Via these catalytic activities and participation ...