Browsing by Keyword "O-GlcNAc"
Now showing items 1-3 of 3
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Engineering a proximity-directed O-GlcNAc transferase to control O-GlcNAc signaling
(2021-11-16)O-GlcNAc is a ubiquitous monosaccharide posttranslational modification analogous to phosphorylation found on thousands of nuclear and cytoplasmic proteins involved in every major cellular process. Dysregulation of O-GlcNAc ... -
O-GlcNAc modification of casein kinase 2 alpha alters the phosphoproteome
(2022-05-12)Post-translational modifications govern protein function and are paramount to many signaling networks in cells. How different post-translational modifications intersect to result in complex signaling outcomes represents a ... -
O-GlcNAcylation regulates breast cancer metastasis via SIRT1 modulation of FOXM1 pathway
(2016)Tumors utilize aerobic glycolysis to support growth and invasion. However, the molecular mechanisms that link metabolism with invasion are not well understood. The nutrient sensor O-linked-β-N-acetylglucosamine (O-GlcNAc) ...