Browsing by Keyword "N-cadherin"
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Metformin represses cancer cells via alternate pathways in N-cadherin expressing vs. N-cadherin deficient cells
(Impact Journals LLC, 2015)Metformin has emerged as a potential anticancer agent. Here, we demonstrate that metformin plays an anti-tumor role via repressing N-cadherin, independent of AMPK, in wild-type N-cadherin cancer cells. Ectopic-expression ... -
N-cadherin prevents the premature differentiation of anterior heart field progenitors in the pharyngeal mesodermal microenvironment
(Nature Publishing Group, 2014)The cardiac progenitor cells (CPCs) in the anterior heart field (AHF) are located in the pharyngeal mesoderm (PM), where they expand, migrate and eventually differentiate into major cell types found in the heart, including ...