Now showing items 1-2 of 2

    • DNA METHYLATION BY DNMT1 AND DNMT3b METHYLTRANSFERASES IS DRIVEN BY THE MUC1-C ONCOPROTEIN IN HUMAN CARCINOMA CELLS 

      Rajabi, Hasan; Tagde, Ashujit; Alam, Maroof; Bouillez, Audrey; Pitroda, Sean; Suzuki, Yozo; Kufe, Donald (2016)
      Aberrant expression of the DNA methyltransferases (DNMTs) and disruption of DNA methylation patterns are associated with carcinogenesis and cancer cell survival. The oncogenic MUC1-C protein is aberrantly overexpressed in ...
    • Heme oxygenase-1 in macrophages controls prostate cancer progression 

      Nemeth, Zsuzsanna; Li, Mailin; Csizmadia, Eva; Döme, Balazs; Johansson, Martin; Persson, Jenny Liao; Seth, Pankaj; Otterbein, Leo; Wegiel, Barbara (Impact Journals LLC, 2015)
      Innate immune cells strongly influence cancer growth and progression via multiple mechanisms including regulation of epithelial to mesenchymal transition (EMT). In this study, we investigated whether expression of the ...