Browsing by Title

Now showing items 22402-22421 of 57070

    • Gut bacterial metabolism of corticoids and other host-produced steroids 

      McCurry, Megan D. (2023-06-01)
      The human gut microbiome is important to human health, and disruptions in the human gut microbiota community are linked to a variety of human disease states. However, until recently, few studies have examined how the gut ...

    • Gut bacterial phospholipase Ds support disease-associated metabolism by generating choline 

      Chittim, Carina; Martinez del Campo, Ana; Balskus, Emily (Springer Nature, 2018-11-19)

    • A gut feeling about arthritis 

      Mathis, Diane (eLife Sciences Publications, Ltd, 2013)
      The gut microbiota of patients recently diagnosed with rheumatoid arthritis is enriched in microbes belonging to the Prevotella genus.

    • Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention 

      Liu, Ruixin; Hong, Jie; Xu, Xiaoqiang; Feng, Qiang; Zhang, Dongya; Gu, Yanyun; Shi, Juan; Zhao, Shaoqian; Liu, Wen; Wang, Xiaokai; Xia, Huihua; Liu, Zhipeng; Cui, Bin; Liang, Peiwen; Xi, Liuqing; Jin, Jiabin; Ying, Xiayang; Wang, Xiaolin; Zhao, Xinjie; Li, Wanyu; Jia, Huijue; Lan, Zhou; Li, Fengyu; Wang, Rui; Sun, Yingkai; Yang, Minglan; Shen, Yuxin; Jie, Zhuye; Li, Junhua; Chen, Xiaomin; Zhong, Huanzi; Xie, Hailiang; Zhang, Yifei; Gu, Weiqiong; Deng, Xiaxing; Shen, Baiyong; Xu, Xun; Yang, Huanming; Xu, Guowang; Bi, Yufang; Lai, Shenghan; Wang, Jian; Qi, Lu; Madsen, Lise; Wang, Jiqiu; Ning, Guang; Kristiansen, Karsten; Wang, Weiqing (Springer Nature, 2017)

    • Gut Microbiome Composition and Attention Deficit Hyperactivity Disorder 

      Bimm, Alexander Jacob (2022-05-23)
      The human gut microbiome may play a key role in mental health as researchers continue to elucidate new pathways of communication between it and the central nervous system. This axis opens a new avenue of research aiming ...

    • Gut microbiome composition and function in experimental colitis during active disease and treatment-induced remission 

      Rooks, Michelle G; Veiga, Patrick; Wardwell-Scott, Leslie H; Tickle, Timothy; Segata, Nicola; Michaud, Monia; Gallini, Carey Ann; Beal, Chloé; van Hylckama-Vlieg, Johan ET; Ballal, Sonia Arora; Morgan, Xochitl C; Glickman, Jonathan Neil; Gevers, Dirk; Huttenhower, Curtis; Garrett, Wendy S. (Springer Nature, 2014)
      Dysregulated immune responses to gut microbes are central to inflammatory bowel disease (IBD), and gut microbial activity can fuel chronic inflammation. Examining how IBD-directed therapies influence gut microbiomes may ...

    • The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids 

      Fu, Jingyuan; Bonder, Marc Jan; Cenit, María Carmen; Tigchelaar, Ettje F.; Maatman, Astrid; Dekens, Jackie A.M.; Brandsma, Eelke; Marczynska, Joanna; Imhann, Floris; Weersma, Rinse K.; Franke, Lude; Poon, Tiffany W.; Xavier, Ramnik J.; Gevers, Dirk; Hofker, Marten H.; Wijmenga, Cisca; Zhernakova, Alexandra (Lippincott Williams & Wilkins, 2015)
      Rationale: Evidence suggests that the gut microbiome is involved in the development of cardiovascular disease, with the host–microbe interaction regulating immune and metabolic pathways. However, there was no firm evidence ...

    • The Gut Microbiome Modulates the Protective Association Between a Mediterranean Diet and Cardiometabolic Disease Risk 

      Wang, Dong; Nguyen, Long; Li, Yanping; Yan, Yan; Ma, Wenjie; Rinott, Ehud; Ivey, Kerry; Shai, Iris; Willett, Walter; Hu, Frank; Rimm, Eric; Stampfer, Meir; Chan, Andrew; Huttenhower, Curtis (Springer Science and Business Media LLC, 2021-02-11)
      Few studies have formally tested the interaction between diet and the gut microbiome in the context of cardiometabolic health, particularly with the microbiome considered as a potential mediator rather than a target of ...

    • The Gut Microbiota and Mucosal T Cells 

      Smith, Patrick M.; Garrett, Wendy S. (Frontiers Media SA, 2011)
      It is intuitive that immune cells in the gut may require microbiota-derived cues for their differentiation. The proximity between host and microbe in the intestine would seemingly necessitate co-adaptation. However, it has ...

    • The Gut Microbiota Is Associated With Immune Cell Dynamics in Humans 

      Schluter, Jonas; Peled, Jonathan; Taylor, Bradford; Markey, Kate; Smith, Melody; Taur, Ying; Niehus, Rene; Staffas, Anna; Dai, Anqi; Fontana, Emily; Amoretti, Luigi; Wright, Roberta; Morjaria, Sejal; Fenelus, Maly; Pessin, Melissa; Chao, Nelson; Lew, Meagan; Bohannon, Lauren; Bush, Amy; Sung, Anthony; Hohl, Tobias; Perales, Miguel-Angel; van den Brink, Marcel R.M.; Xavier, Joao; Xavier (Nature Research, 2020-11-25)
      The gut microbiota influences development1–3 and homeostasis4–7 of the mammalian immune system, and is associated with human inflammatory-8 and immune diseases9,10 as well as patients’ responses to immunotherapy11–14. ...

    • Gut Microbiota Metabolites of Dietary Lignans and Risk of Type 2 Diabetes: A Prospective Investigation in Two Cohorts of U.S. Women 

      Sun, Qi; Wedick, Nicole; Pan, An; Townsend, Mary; Cassidy, Aedin; Franke, Adrian; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Hu, Frank; van Dam, Rob M. (American Diabetes Association, 2014)
      OBJECTIVE To examine urinary levels of enterolactone and enterodiol, intestinal microbial metabolites of dietary lignans, in relation to type 2 diabetes (T2D) risk. RESEARCH DESIGN AND METHODS Urinary concentrations of the ...

    • Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes 

      Sanmarco, Liliana; Wheeler, Michael; Gutiérrez-Vázquez, Cristina; Polonio, Carolina Manganeli; Linnerbauer, Mathias; Pinho-Ribeiro, Felipe A.; Li, Zhaorong; Giovannoni, Federico; Batterman, Katelyn V.; Scalisi, Giulia; Zandee, Stephanie E. J.; Heck, Evelyn S.; Alsuwailm, Moneera; Rosene, Douglas L.; Becher, Burkhard; Chiu, Isaac M.; Prat, Alexandre; Quintana, Francisco J. (Springer Science and Business Media LLC, 2021-01-06)

    • Gut-Microbiome-Related LCT Genotype and 2-Year Changes in Body Composition and Fat Distribution: The POUNDS Lost Trial 

      Heianza, Yoriko; Sun, Dianjianyi; Ma, Wenjie; Zheng, Yan; Champagne, Catherine M.; Bray, George A.; Sacks, Frank; Qi, Lu (Springer Science and Business Media LLC, 2018-02-26)
      Background/Objectives Gut microbiome regulates host energy metabolism and adiposity. A recent study identified a genome-wide significant variant in the lactase (LCT) gene that determines gut microbiome abundance. We ...

    • GUTs and exceptional branes in F-theory — I 

      Beasley, Chris; Heckman, Jonathan J.; Vafa, Cumrun (Springer Verlag, 2009)

    • GW8510 Increases Insulin Expression in Pancreatic Alpha Cells through Activation of p53 Transcriptional Activity 

      Fomina-Yadlin, Dina; Kubicek, Stefan; Vetere, Amedeo; He, Kaihui Hu; Schreiber, Stuart L.; Wagner, Bridget K. (Public Library of Science, 2012)
      Background: Expression of insulin in terminally differentiated non-beta cell types in the pancreas could be important to treating type-1 diabetes. Previous findings led us to hypothesize involvement of kinase inhibition ...

    • GWAS Identifies Novel Susceptibility Loci on 6p21.32 and 21q21.3 for Hepatocellular Carcinoma in Chronic Hepatitis B Virus Carriers 

      Li, Shengping; Qian, Ji; Zhao, Wanting; Dai, Juncheng; Bei, Jin-Xin; Foo, Jia Nee; McLaren, Paul J.; Li, Zhiqiang; Yang, Jingmin; Shen, Feng; Yang, Jiamei; Li, Shuhong; Pan, Shandong; Li, Wenjin; Zhai, Xiangjun; Zhou, Boping; Shi, Lehua; Chen, Xinchun; Chu, Minjie; Yan, Yiqun; Cheng, Shuqun; Shen, Jiawei; Jia, Weihua; Liu, Jibin; Yang, Jiahe; Wen, Zujia; Li, Aijun; Zhang, Guoliang; Luo, Xianrong; Qin, Hongbo; Chen, Minshan; Lin, Dongxin; Shen, Hongbing; Wang, Hongyang; Zeng, Yi-Xin; Wu, Mengchao; Hu, Zhibin; Shi, Yongyong; Liu, Jianjun; Zhou, Weiping; Yang, Yuan; Liu, Li; Wang, Yi; Wang, Jun; Zhang, Ying; Wang, Hua; Jin, Li; He, Lin; de Bakker, Paul I. Wen (Public Library of Science, 2012)
      Genome-wide association studies (GWAS) have recently identified KIF1B as susceptibility locus for hepatitis B virus (HBV)–related hepatocellular carcinoma (HCC). To further identify novel susceptibility loci associated ...

    • GWAS in IMIDs 

      Plenge, Robert M. (BioMed Central, 2010)

    • GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer 

      Pharoah, Paul D. P.; Tsai, Ya-Yu; Ramus, Susan J.; Phelan, Catherine M.; Goode, Ellen L.; Lawrenson, Kate; Price, Melissa; Fridley, Brooke L.; Tyrer, Jonathan P.; Shen, Howard; Weber, Rachel; Karevan, Rod; Larson, Melissa C.; Song, Honglin; Tessier, Daniel C.; Bacot, François; Vincent, Daniel; Cunningham, Julie M.; Dennis, Joe; Dicks, Ed; Aben, Katja K.; Anton-Culver, Hoda; Antonenkova, Natalia; Armasu, Sebastian M.; Baglietto, Laura; Bandera, Elisa V.; Beckmann, Matthias W.; Birrer, Michael J.; Bloom, Greg; Bogdanova, Natalia; Brenton, James D.; Brinton, Louise A.; Brooks-Wilson, Angela; Brown, Robert; Butzow, Ralf; Campbell, Ian; Carney, Michael E; Carvalho, Renato S.; Chang-Claude, Jenny; Chen, Y. Anne; Chen, Zhihua; Chow, Wong-Ho; Cicek, Mine S.; Coetzee, Gerhard; Cook, Linda S.; Cramer, Daniel W.; Cybulski, Cezary; Dansonka-Mieszkowska, Agnieszka; Despierre, Evelyn; Doherty, Jennifer A; Dörk, Thilo; du Bois, Andreas; Dürst, Matthias; Eccles, Diana; Edwards, Robert; Ekici, Arif B.; Fasching, Peter A.; Fenstermacher, David; Flanagan, James; Gao, Yu-Tang; Garcia-Closas, Montserrat; Gentry-Maharaj, Aleksandra; Giles, Graham; Gjyshi, Anxhela; Gore, Martin; Gronwald, Jacek; Guo, Qi; Halle, Mari K; Harter, Philipp; Hein, Alexander; Heitz, Florian; Hillemanns, Peter; Hoatlin, Maureen; Høgdall, Estrid; Høgdall, Claus K.; Hosono, Satoyo; Jakubowska, Anna; Jensen, Allan; Kalli, Kimberly R.; Karlan, Beth Y.; Kelemen, Linda E.; Kiemeney, Lambertus A.; Kjaer, Susanne Krüger; Konecny, Gottfried E.; Krakstad, Camilla; Kupryjanczyk, Jolanta; Lambrechts, Diether; Lambrechts, Sandrina; Le, Nhu D.; Lee, Nathan; Lee, Janet; Leminen, Arto; Lim, Boon Kiong; Lissowska, Jolanta; Lubiński, Jan; Lundvall, Lene; Lurie, Galina; Massuger, Leon F.A.G.; Matsuo, Keitaro; McGuire, Valerie; McLaughlin, John R; Menon, Usha; Modugno, Francesmary; Moysich, Kirsten B.; Nakanishi, Toru; Narod, Steven A.; Ness, Roberta B.; Nevanlinna, Heli; Nickels, Stefan; Noushmehr, Houtan; Odunsi, Kunle; Olson, Sara; Orlow, Irene; Paul, James; Pejovic, Tanja; Pelttari, Liisa M; Permuth-Wey, Jenny; Pike, Malcolm C; Poole, Elizabeth M; Qu, Xiaotao; Risch, Harvey A.; Rodriguez-Rodriguez, Lorna; Rossing, Mary Anne; Rudolph, Anja; Runnebaum, Ingo; Rzepecka, Iwona K; Salvesen, Helga B.; Schwaab, Ira; Severi, Gianluca; Shen, Hui; Shridhar, Vijayalakshmi; Shu, Xiao-Ou; Sieh, Weiva; Southey, Melissa C.; Spellman, Paul; Tajima, Kazuo; Teo, Soo-Hwang; Terry, Kathryn L.; Thompson, Pamela J; Timorek, Agnieszka; Tworoger, Shelley S.; van Altena, Anne M.; Berg, David Van Den; Vergote, Ignace; Vierkant, Robert A.; Vitonis, Allison F.; Wang-Gohrke, Shan; Wentzensen, Nicolas; Whittemore, Alice S.; Wik, Elisabeth; Winterhoff, Boris; Woo, Yin Ling; Wu, Anna H; Yang, Hannah P.; Zheng, Wei; Ziogas, Argyrios; Zulkifli, Famida; Goodman, Marc T.; Hall, Per; Easton, Douglas F; Pearce, Celeste L; Berchuck, Andrew; Chenevix-Trench, Georgia; Iversen, Edwin; Monteiro, Alvaro N.A.; Gayther, Simon A.; Schildkraut, Joellen M.; Sellers, Thomas A. (2013)
      Genome wide association studies (GWAS) have identified four susceptibility loci for epithelial ovarian cancer (EOC) with another two loci being close to genome-wide significance. We pooled data from a GWAS conducted in ...

    • GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment 

      Rietveld, Cornelius A.; Medland, Sarah E.; Derringer, Jaime; Yang, Jian; Esko, Tonu; Martin, Nicolas W.; Westra, Harm-Jan; Shakhbazov, Konstantin; Abdellaoui, Abdel; Agrawal, Arpana; Albrecht, Eva; Alizadeh, Behrooz Z.; Amin, Najaf; Barnard, John; Baumeister, Sebastian E.; Benke, Kelly S.; Bielak, Lawrence F.; Boatman, Jeffrey A.; Boyle, Patricia A.; Davies, Gail; de Leeuw, Christiaan; Eklund, Niina; Evans, Daniel S.; Ferhmann, Rudolf; Fischer, Krista; Gieger, Christian; Gjessing, Håkon K.; Hagg, Sara; Harris, Jennifer R.; Hayward, Caroline; Holzapfel, Christina; Ibrahim-Verbaas, Carla A.; Ingelsson, Erik; Jacobsson, Bo; Joshi, Peter K.; Jugessur, Astanand; Kaakinen, Marika; Kanoni, Stavroula; Karjalainen, Juha; Kolcic, Ivana; Kristiansson, Kati; Kutalik, Zoltán; Lahti, Jari; Lee, Sang H.; Lin, Peng; Lind, Penelope A.; Liu, Yongmei; Lohman, Kurt; Loitfelder, Marisa; McMahon, George; Vidal, Pedro Marques; Meirelles, Osorio; Milani, Lili; Myhre, Ronny; Nuotio, Marja-Liisa; Oldmeadow, Christopher J.; Petrovic, Katja E.; Peyrot, Wouter J.; Polašek, Ozren; Quaye, Lydia; Reinmaa, Eva; Rice, John P.; Rizzi, Thais S.; Schmidt, Helena; Schmidt, Reinhold; Smith, Albert V.; Smith, Jennifer A.; Tanaka, Toshiko; Terracciano, Antonio; van der Loos, Matthijs J. H. M.; Vitart, Veronique; Völzke, Henry; Wellmann, Jürgen; Yu, Lei; Zhao, Wei; Allik, Jüri; Attia, John R.; Bandinelli, Stefania; Bastardot, François; Beauchamp, Jonathan; Bennett, David A.; Berger, Klaus; Bierut, Laura J.; Boomsma, Dorret I.; Bültmann, Ute; Campbell, Harry; Chabris, Christopher; Cherkas, Lynn; Chung, Mina K.; Cucca, Francesco; de Andrade, Mariza; De Jager, Philip Lawrence; De Neve, Jan-Emmanuel; Deary, Ian J.; Dedoussis, George V.; Deloukas, Panos; Dimitriou, Maria; Eiríksdóttir, Guðný; Elderson, Martin F.; Eriksson, Johan G.; Evans, David M.; Faul, Jessica D.; Ferrucci, Luigi; Garcia, Melissa E.; Grönberg, Henrik; Guðnason, Vilmundur; Hall, Per; Harris, Juliette M.; Harris, Tamara B.; Hastie, Nicholas D.; Heath, Andrew C.; Hernandez, Dena G.; Hoffmann, Wolfgang; Hofman, Adriaan; Holle, Rolf; Holliday, Elizabeth G.; Hottenga, Jouke-Jan; Iacono, William G.; Illig, Thomas; Järvelin, Marjo-Riitta; Kähönen, Mika; Kaprio, Jaakko; Kirkpatrick, Robert M.; Kowgier, Matthew; Latvala, Antti; Launer, Lenore J.; Lawlor, Debbie A.; Lehtimäki, Terho; Li, Jingmei; Lichtenstein, Paul; Lichtner, Peter; Liewald, David C.; Madden, Pamela A.; Magnusson, Patrik K. E.; Makinen, Tomi E.; Masala, Marco; McGue, Matt; Metspalu, Andres; Mielck, Andreas; Miller, Michael B.; Montgomery, Grant W.; Mukherjee, Sutapa; Nyholt, Dale R.; Oostra, Ben A.; Palmer, Lyle J.; Palotie, Aarno; Penninx, Brenda W. J. H.; Perola, Markus; Peyser, Patricia A.; Preisig, Martin; Räikkönen, Katri; Raitakari, Olli T.; Realo, Anu; Ring, Susan M.; Ripatti, Samuli; Rivadeneira, Fernando; Rudan, Igor; Rustichini, Aldo; Salomaa, Veikko; Sarin, Antti-Pekka; Schlessinger, David; Scott, Rodney J.; Snieder, Harold; St Pourcain, Beate; Starr, John M.; Sul, Jae Hoon; Surakka, Ida; Svento, Rauli; Teumer, Alexander; Tiemeier, Henning; van Rooij, Frank J. A.; Van Wagoner, David R.; Vartiainen, Erkki; Viikari, Jorma; Vollenweider, Peter; Vonk, Judith M.; Waeber, Gérard; Weir, David R.; Wichmann, H.-Erich; Widen, Elisabeth; Willemsen, Gonneke; Wilson, James F.; Wright, Alan F.; Conley, Dalton; Davey-Smith, George; Franke, Lude; Groenen, Patrick J. F.; Hofman, Albert; Johannesson, Magnus; Kardia, Sharon L. R.; Krueger, Robert F.; Laibson, David I.; Martin, Nicholas G.; Meyer, Michelle N.; Posthuma, Danielle; Thurik, A. Roy; Timpson, Nicholas J.; Uitterlinden, André G.; van Duijn, Cornelia M.; Visscher, Peter M.; Benjamin, Daniel J.; Cesarini, David; Koellinger, Philipp D. (American Association for the Advancement of Science (AAAS), 2013)
      A genome-wide association study (GWAS) of educational attainment was conducted in a discovery sample of 101,069 individuals and a replication sample of 25,490. Three independent single-nucleotide polymorphisms (SNPs) are ...

    • GWAS of Follicular Lymphoma Reveals Allelic Heterogeneity at 6p21.32 and Suggests Shared Genetic Susceptibility with Diffuse Large B-Cell Lymphoma 

      Smedby, Karin E.; Foo, Jia Nee; Skibola, Christine F.; Darabi, Hatef; Conde, Lucia; Hjalgrim, Henrik; Kumar, Vikrant; Chang, Ellen T.; Rothman, Nathaniel; Cerhan, James R.; Brooks-Wilson, Angela R.; Rehnberg, Emil; Irwan, Ishak D.; Ryder, Lars P.; Bracci, Paige M.; Agana, Luz; Riby, Jacques; Cozen, Wendy; Hartge, Patricia; Morton, Lindsay M.; Severson, Richard K.; Slager, Susan L.; Fredericksen, Zachary S.; Novak, Anne J.; Kay, Neil E.; Habermann, Thomas M.; Armstrong, Bruce; Kricker, Anne; Milliken, Sam; Purdue, Mark P.; Vajdic, Claire M.; Boyle, Peter; Lan, Qing; Zahm, Shelia H.; Zhang, Yawei; Zheng, Tongzhang; Leach, Stephen; Spinelli, John J.; Smith, Martyn T.; Chanock, Stephen J.; Padyukov, Leonid; Alfredsson, Lars; Klareskog, Lars; Glimelius, Bengt; Melbye, Mads; Liu, Edison T.; Humphreys, Keith; Liu, Jianjun; Gibson, Greg; Brown, Peter N.; Davis, Scott; Wang, Sophia S.; Adami, Hans-Olov (Public Library of Science, 2011)
      Non-Hodgkin lymphoma (NHL) represents a diverse group of hematological malignancies, of which follicular lymphoma (FL) is a prevalent subtype. A previous genome-wide association study has established a marker, rs10484561 ...