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Now showing items 18497-18516 of 57074
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The Extracellular Matrix of Staphylococcus aureus Biofilms Comprises Cytoplasmic Proteins That Associate with the Cell Surface in Response to Decreasing pH
(American Society of Microbiology, 2014)ABSTRACT Biofilm formation by Staphylococcus aureus involves the formation of an extracellular matrix, but the composition of this matrix has been uncertain. Here we report that the matrix is largely composed of cytoplasmic ... -
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins
(Oxford University Press, 2016)Aims Extracellular matrix remodelling has been implicated in a number of vascular conditions, including venous hypertension and varicose veins. However, to date, no systematic analysis of matrix remodelling in human veins ... -
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver
(BioMed Central, 2014)Background: Colorectal cancer is the third most frequently diagnosed cancer and the third cause of cancer deaths in the United States. Despite the fact that tumor cell-intrinsic mechanisms controlling colorectal carcinogenesis ... -
Extracellular matrix stiffness causes systematic variations in proliferation and chemosensitivity in myeloid leukemias
(National Academy of Sciences, 2016)Extracellular matrix stiffness influences biological functions of some tumors. However, it remains unclear how cancer subtypes with different oncogenic mutations respond to matrix stiffness. In addition, the relevance of ... -
Extracellular Microvesicle Production by Human Eosinophils Activated by “Inflammatory” Stimuli
(Frontiers Media S.A., 2016)A key function of human eosinophils is to secrete cytokines, chemokines and cationic proteins, trafficking, and releasing these mediators for roles in inflammation and other immune responses. Eosinophil activation leads ... -
Extracellular RNAs: development as biomarkers of human disease
(Co-Action Publishing, 2015)Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as biomarkers in human disease are described. These studies, funded by the NIH Common Fund Extracellular RNA Communication Program, ... -
Extracellular Vesicles and Their Convergence with Viral Pathways
(Hindawi Publishing Corporation, 2012)Extracellular vesicles (microvesicles), such as exosomes and shed microvesicles, contain a variety of molecules including proteins, lipids, and nucleic acids. Microvesicles appear mostly to originate from multivesicular ... -
Extracellular vesicles, tissue factor, cancer and thrombosis – discussion themes of the ISEV 2014 Educational Day
(Co-Action Publishing, 2015)Although the association between cancer and venous thromboembolism (VTE) has long been known, the mechanisms are poorly understood. Circulating tissue factor–bearing extracellular vesicles have been proposed as a possible ... -
Extracranial injections of botulinum neurotoxin type A inhibit intracranial meningeal nociceptors’ responses to stimulation of TRPV1 and TRPA1 channels: Are we getting closer to solving this puzzle?
(SAGE Publications, 2016)Background: Administration of onabotulinumtoxinA (BoNT-A) to peripheral tissues outside the calvaria reduces the number of days chronic migraine patients experience headache. Because the headache phase of a migraine attack, ... -
Extracting All the Randomness and Reducing the Error in Trevisan's Extractors
(Elsevier, 2002)We give explicit constructions of extractors which work for a source of any min-entropy on strings of length n. These extractors can extract any constant fraction of the min-entropy using O(log<sup>2</sup><i>n</i>) additional ... -
Extracting black-hole rotational energy: The generalized Penrose process
(American Physical Society (APS), 2014)In the case involving particles the necessary and sufficient condition for the Penrose process to extract energy from a rotating black hole is absorption of particles with negative energies and angular momenta. No torque ... -
Extracting Physician Group Intelligence from Electronic Health Records to Support Evidence Based Medicine
(Public Library of Science, 2013)Evidence-based medicine employs expert opinion and clinical data to inform clinical decision making. The objective of this study is to determine whether it is possible to complement these sources of evidence with information ... -
Extracting Randomness from Samplable Distributions
(IEEE Computer Society Press, 2000)The standard notion of a randomness extractor is a procedure which converts any weak source of randomness into an almost uniform distribution. The conversion necessarily uses a small amount of pure randomness, which can ... -
Extracting Reparative Power: redistributing power in post-mining transition
(2023-05-17)This thesis explores landscape as a medium for ecological reparation in the energy transition by pairing renewable energy infrastructure with regenerative agriculture. The project's goal is to visualize the reorganization ... -
Extracting Sequence Features to Predict Protein–DNA Interactions: A Comparative Study
(Oxford University Press, 2008)Predicting how and where proteins, especially transcription factors (TFs), interact with DNA is an important problem in biology. We present here a systematic study of predictive modeling approaches to the TF–DNA binding ... -
Extracting Spatiotemporal Word and Semantic Representations from Multiscale Neurophysiological Recordings in Humans
(2012-09-13)With the recent advent of neuroimaging techniques, the majority of the research studying the neural basis of language processing has focused on the localization of various lexical and semantic functions. Unfortunately, ... -
Extracting the Density Profile of an Electronic Wave Function in a Quantum Dot
(American Physical Society, 2011)We use a model of a one-dimensional nanowire quantum dot to demonstrate the feasibility of a scanning probe microscope (SPM) imaging technique that can extract both the energy of an electron state and the amplitude of its ... -
Extraction and sequencing of human and Neanderthal mature enamel proteins using MALDI-TOF/TOF MS
(Elsevier BV, 2009)We report here the first results of a method to extract and sequence mature enamel proteins from modern human and Neanderthal tooth enamel. Using MALDI-TOF/TOF mass spectrometry and a combination of direct sequencing and ... -
The Extraction of Depth Structure from Shading and Texture in the Macaque Brain
(Public Library of Science, 2009)We used contrast-agent enhanced functional magnetic resonance imaging (fMRI) in the alert monkey to map the cortical regions involved in the extraction of 3D shape from the monocular static cues, texture and shading. As ... -
Extraction of heart rate from functional near-infrared spectroscopy in infants
(SPIE-Intl Soc Optical Eng, 2014)Changes in heart rate are a useful physiological measure in infant studies. We present an algorithm for calculating the heart rate (HR) from oxyhemoglobin pulsation in functional near-infrared spectroscopy (fNIRS) signals. ...