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Now showing items 11053-11072 of 57070
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Cytosolic 5′-Nucleotidase 1A Autoimmunity in Sporadic Inclusion Body Myositis
(Wiley, 2013-03)Objective We previously identified a circulating autoantibody against a 43 kDa muscle autoantigen in sporadic inclusion body myositis (IBM) and demonstrated the feasibility of an IBM diagnostic blood test. Here, we sought ... -
Cytosolic Phospholipase A2 Protein as a Novel Therapeutic Target for Spinal Cord Injury
(BlackWell Publishing Ltd, 2014)Objective: The objective of this study was to investigate whether cytosolic phospholipase A2 (cPLA2), an important isoform of PLA2 that mediates the release of arachidonic acid, plays a role in the pathogenesis of spinal ... -
Cytotoxicity of Botulinum Neurotoxins Reveals a Direct Role of Syntaxin 1 and SNAP-25 in Neuron Survival
(2014)Botulinum neurotoxins (BoNT/A-G) are well-known to act by blocking synaptic vesicle exocytosis. Whether BoNTs disrupt additional neuronal functions has not been addressed. Here we report that cleavage of syntaxin 1 (Syx ... -
Cytotoxicity of Hydrogen Peroxide Produced by Enterococcus faecium
(American Society for Microbiology, 2004)Although the opportunistic bacterial pathogen Enterococcus faecium is a leading source of nosocomial infections, it appears to lack many of the overt virulence factors produced by other bacterial pathogens, and the underlying ... -
C–H Functionalization Catalysis via Transition Metal Stabilized Ligand-Based Radicals
(2021-04-23)Two catalytic systems exploiting the capability of introducing functionalities into C–H bonds using transition metal stabilized ligand-based radicals were explored. The first system utilizes sterically accessible bidentate ... -
D,L-Cyclic Peptides as Structural Materials
(2015-04-17)The bioengineer has a choice of building with proteins, peptides, polymers, nucleic acids, lipids, metals and minerals, each class containing tremendous diversity within its category. While the platforms are diverse, they ... -
D--branes and Spinning Black Holes
(Elsevier, 1996)We obtain a new class of spinning charged extremal black holes in five dimensions, considered both as classical configurations and in the Dirichlet (D)-brane representation. The degeneracy of states is computed from the ... -
D-Amino Acids Indirectly Inhibit Biofilm Formation in Bacillus subtilis by Interfering with Protein Synthesis
(American Society for Microbiology, 2013)The soil bacterium Bacillus subtilis forms biofilms on surfaces and at air-liquid interfaces. It was previously reported that these biofilms disassemble late in their life cycle and that conditioned medium from late-stage ... -
D-brane Construction of the 5D NHEK Dual
(Springer-Verlag, 2012)Extremal but non-supersymmetric charged black holes with \(SU(2)_L\) spin in IIB string theory compactified to five dimensions on \(K^3 \times S^1\) are considered. These have a near-horizon or NHEK region with an enhanced ... -
D-brane Deconstructions in IIB Orientifolds
(Institute of Physics, 2009)With model building applications in mind, we collect and develop basic techniques to analyze the landscape of D7-branes in type IIB compact Calabi-Yau orientifolds, in three different pictures: F-theory, the D7 worldvolume ... -
d-Cycloserine enhances durability of social skills training in autism spectrum disorder
(BioMed Central, 2017)Background: d-Cycloserine (DCS) enhances extinction learning across species, but it has proven challenging to identify consistent benefit of DCS when added to therapeutic interventions. We conducted a placebo-controlled ... -
d-Dimer elevation and adverse outcomes
(Springer US, 2014)d-Dimer is a biomarker of fibrin formation and degradation. While a d-dimer within normal limits is used to rule out the diagnosis of deep venous thrombosis and pulmonary embolism among patients with a low clinical probability ... -
D-helix influences dimerization of the ATP-binding cassette (ABC) transporter associated with antigen processing 1 (TAP1) nucleotide-binding domain
(Public Library of Science (PLoS), 2017)ATP-binding cassette (ABC) transporters form a large family of transmembrane importers and exporters. Using two nucleotide-binding domains (NBDs), which form a canonical ATP-sandwich dimer at some point within the transport ... -
D-instantons and String Field Theory
(2023-05-12)In this thesis, we study D-instanton contributions to supergraviton scattering amplitudes in ten-dimensional type IIB superstring theory beyond the leading non-perturbative order. Our computation is based on the ... -
D-modules and finite monodromy
(Springer Nature, 2016)We investigate an analogue of the Grothendieck p-curvature conjecture, where the vanishing of the p-curvature is replaced by the stronger condition, that the module with connection mod p underlies a XDX -module structure. ... -
D-Modules on Spaces of Rational Maps and on Other Generic Data
(2012-12-13)Fix an algebraic curve X. We study the problem of parametrizing geometric data over X, which is only generically defined. E.g., parametrizing generically defined maps from X to a fixed target scheme Y. There are three methods ... -
D-Modules on the Affine Flag Variety and Representations of Affine Kac-Moody Algebras
(American Mathematical Society, 2009)The present paper studies the connection between the category of modules over the affine Kac-Moody Lie algebra at the critical level, and the category of D-modules on the affine flag scheme \(G((t))/I\), where \(I\) is the ... -
D-π-A Dye System Containing Cyano-Benzoic Acid as Anchoring Group for Dye-Sensitized Solar Cells
(American Chemical Society, 2011) -
D. H. Lawrence and Studies in Classic American Literature
Although D. H. Lawrence is still considered by many critics one of the most significant English writers of the early twentieth century, a general perception of racist and misogynist tendencies in Lawrence's writing has ... -
D. H. Lawrence and Studies in Classic American Literature
Although D. H. Lawrence is still considered by many critics one of the most significant English writers of the early twentieth century, a general perception of racist and misogynist tendencies in Lawrence's writing has ...