Browsing by Title
Now showing items 14278-14297 of 56955
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The E-NTPDase Family of Ectonucleotidases: Structure Function Relationships and Pathophysiological Significance
(Springer Netherlands, 2006)Ectonucleotidases are ectoenzymes that hydrolyze extracellular nucleotides to the respective nucleosides. Within the past decade, ectonucleotidases belonging to several enzyme families have been discovered, cloned and ... -
E-Park: Automated-Ticketing Parking Meter System
(2015-06-26)E-Park is an electronic parking meter system which enables real-time ticketing of illegally parked vehicles. The system is a drop-in replacement for existing curb-side parking meters. It consists of lowpower front-end ... -
E-Readers Are More Effective than Paper for Some with Dyslexia
(Public Library of Science, 2013)E-readers are fast rivaling print as a dominant method for reading. Because they offer accessibility options that are impossible in print, they are potentially beneficial for those with impairments, such as dyslexia. Yet, ... -
E-resources in the US university library: Harvard’s case under the pandemic
(J-Stage, 2021)Due to the pandemic, Harvard University swiftly switched its instruction from in-person to remote in the middle of March 2020. The online instruction continues through the fall semester. Providing online resources have ... -
E-selectin inhibition mitigates splenic HSC activation and myelopoiesis in hypercholesterolemic mice with myocardial infarction
(American Heart Association, 2016)Objective Atherosclerosis is a chronic disease characterized by lipid accumulation in the arterial wall. After myocardial infarction (MI), atherosclerotic plaques are infiltrated by inflammatory myeloid cells that aggravate ... -
E-Selectin Mediates Immune Cell Trafficking in Corneal Transplantation
(Ovid Technologies (Wolters Kluwer Health), 2016)Background Immune rejection continues to threaten all tissue transplants. Here we sought to determine whether P- and E- selectin mediate T cell recruitment in corneal transplantation and whether their blockade can reduce ... -
E-strings and N = 4 topological Yang-Mills theories
(Elsevier, 1998)We study certain properties of six-dimensional tensionless E-strings (arising from zero size E-8 instantons). In particular we show that n E-strings form a bound string which carries an E-8 level-n current algebra as well ... -
E. E. Cummings at Harvard: Studies
(Harvard Library, 1976) -
E. E. Cummings at Harvard: Verse, friends, rebellion
(Harvard Library, 1977) -
E. E. Cummings, Painter
(Harvard Library, 1975) -
E. P. Thompson, Politics and History: Writing Social History Fifty Years after The Making of the English Working Class
(Oxford University Press (OUP), 2015) -
E1A-engineered human umbilical cord mesenchymal stem cells as carriers and amplifiers for adenovirus suppress hepatocarcinoma in mice
(Impact Journals LLC, 2016)Gene therapy is an attractive approach for hepatocellular carcinoma (HCC) patients. Nevertheless, efficient transgene delivery remains a challenge. In this study, we explored a new targeted system based on human umbilical ... -
E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system
(National Academy of Sciences, 2006)In cells expressing human cytornegalovirus US11 protein, newly synthesized MHC class I heavy chains (HCs) are rapidly dislocated from the endoplasmic reticulum (ER) and degraded in the cytosol, a process that is similar ... -
E2a/Pbx1 Induces the Rapid Proliferation of Stem Cell Factor-Dependent Murine Pro-T Cells That Cause Acute T-Lymphoid or Myeloid Leukemias in Mice
(American Society for Microbiology, 2004)Oncoprotein E2a/Pbx1 is produced by the t(1;19) chromosomal translocation of human pre-B acute lymphoblastic leukemia. E2a/Pbx1 blocks differentiation of primary myeloid progenitors but, paradoxically, induces apoptosis ... -
E2F and p53 Induce Apoptosis Independently during Drosophila Development but Intersect in the Context of DNA Damage
(Public Library of Science, 2008)In mammalian cells, RB/E2F and p53 are intimately connected, and crosstalk between these pathways is critical for the induction of cell cycle arrest or cell death in response to cellular stresses. Here we have investigated ... -
The E3 ligase adapter cereblon targets the C-terminal cyclic imide degron
(Springer Science and Business Media LLC, 2022-10-19)The E3 ligase substrate adaptor cereblon (CRBN) is a target of thalidomide and lenalidomide,1 which are therapeutic agents used in the treatment of hematopoietic malignancies2-4 and as ligands for targeted protein ... -
E3 ligase Hei10: a multifaceted structure-based signaling molecule with roles within and beyond meiosis
(Cold Spring Harbor Laboratory Press, 2014)Human enhancer of invasion-10 (Hei10) mediates meiotic recombination and also plays roles in cell proliferation. Here we explore Hei10's roles throughout the sexual cycle of the fungus Sordaria with respect to localization ... -
The E3 ubiquitin ligase ZNRF2 is a substrate of mTORC1 and regulates its activation by amino acids
(eLife Sciences Publications, Ltd, 2016)The mechanistic Target of Rapamycin complex 1 (mTORC1) senses intracellular amino acid levels through an intricate machinery, which includes the Rag GTPases, Ragulator and vacuolar ATPase (V-ATPase). The membrane-associated ... -
The earl and the thief: Lord Ashburnham and Count Libri
(Harvard Library, 1969)