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Now showing items 55044-55063 of 57070
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V Gene Diversity Allows the B Cell Receptor to Accommodate Specific Antigen Shapes
(2018-05-04)Forming complementarity to previously unseen foreign material is a key function of the antibody response. The antibody-ligand binding surface is created by a diversity of V gene encoded and non-encoded complementarity ... -
V-TIME: a Treadmill Training Program Augmented by Virtual Reality to Decrease Fall Risk in Older Adults: Study Design of a Randomized Controlled Trial
(BioMed Central, 2013)Background: Recent work has demonstrated that fall risk can be attributed to cognitive as well as motor deficits. Indeed, everyday walking in complex environments utilizes executive function, dual tasking, planning and ... -
The V1647 Orionis (IRAS 05436–0007) Protostar and Its Environment
(IOP Publishing, 2004)We present Sloan Digital Sky Survey (SDSS) and United States Naval Observatory (USNO) observations of the V1647 Ori protostar and its surrounding field near NGC 2068. V1647 Ori, the likely driving source for HH 23, brightened ... -
VAC14 Nucleates a Protein Complex Essential for the Acute Interconversion of PI3P and PI(3,5)P2 in Yeast and Mouse
(Nature Publishing Group, 2008)The signalling lipid PI(3,5)P2 is generated on endosomes and regulates retrograde traffic to the trans-Golgi network. Physiological signals regulate rapid, transient changes in PI(3,5)P2 levels. Mutations that lower PI(3,5)P2 ... -
Vacancy in Silicon Revisited: Structure and Pressure Effects
(American Physical Society, 1998)The structure of the single vacancy in silicon. one of the most common point defects and an important mediator of atomic diffusion, is examined through extensive first principles calculations. We find a hitherto unexpected ... -
Vacant Land Conversion in Detroit, Michigan: A Spatial Analysis of Neighborhood Stabilization and Communal Access
(2017-05-20)This research explores vacant land conversion in Detroit, Michigan and the extent to which vacant land is being utilized towards sustainability through urban agriculture. The main statistical hypotheses of this study are ... -
Vaccination against colonizing bacteria with multiple serotypes
(Proceedings of the National Academy of Sciences, 1997)Conjugate vaccines protect vaccinated individuals against both disease from and nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae. Protection is specific to the capsular serotype(s) included ... -
Vaccination and All-Cause Child Mortality From 1985 to 2011: Global Evidence From the Demographic and Health Surveys
(Oxford University Press (OUP), 2015-10-08)Based on models with calibrated parameters for infection, case fatality rates, and vaccine efficacy, basic childhood vaccinations have been estimated to be highly cost effective. We estimated the association of vaccination ... -
Vaccination Confidence and Parental Refusal/Delay of Early Childhood Vaccines
(Public Library of Science, 2016)Objective: To support efforts to address parental hesitancy towards early childhood vaccination, we sought to validate the Vaccination Confidence Scale using data from a large, population-based sample of U.S. parents. ... -
Vaccination Rates are Associated With Functional Proximity But Not Base Proximity of Vaccination Clinics
(Ovid Technologies (Wolters Kluwer Health), 2016)Background: Routine annual influenza vaccinations are recommended for persons 6 months of age and older, but less than half of US adults get vaccinated. Many employers offer employees free influenza vaccinations at ... -
THE VACCINE ADDITIVE THIMEROSAL: CAUSATION AND COMPENSATION FOR CHILDREN WITH AUTISM
(2003). This Paper explores the complex thimerosal debate. Part II briefly sets out the history of vaccine manufacturers in the last half of the twentieth century culminating with the passage of the Vaccine Act; it also posits ... -
Vaccine Allocation in a Declining Epidemic
(The Royal Society, 2012)Sizeable quantities of 2009 pandemic influenza A/H1N1 (H1N1pdm) vaccine in the USA became available at the end of 2009 when the autumn wave of the epidemic was declining. At that point, risk factors for H1N1-related mortality ... -
Vaccine responses in the context of impaired self-tolerance
(2021-07-12)In the context of HIV vaccine design, broadly-neutralizing antibodies (bnAbs) are those which are able to neutralize a diverse population of HIV variants. The existing global diversity of HIV necessitates that any traditional ... -
Vaccine testing for emerging infections: the case for individual randomisation
(BMJ, 2017)During the 2014-2015 Ebola outbreak in Guinea, Liberia and Sierra Leone, many opposed the use of individually randomised controlled trials to test candidate Ebola vaccines. For a raging fatal disease, they explained, it ... -
Vaccines and The National Vaccine Injury Compensation Program
(2000)The federal government plays a leading role in vaccination by funding vaccine administration and by integrating the immunization efforts of the public and private sectors on national, state and local levels. Congress ... -
Vaccines: Populations, Individuals and Models
(2023-06-01)The 2009 H1N1 influenza and 2019 SARS-CoV-2 pandemics have highlighted the need for control measures against emerging infectious diseases. Vaccines are currently the most effective intervention against these pathogens, ... -
Vaccinia Virus Induces Strong Immunoregulatory Cytokine Production in Healthy Human Epidermal Keratinocytes: a Novel Strategy for Immune Evasion
(American Society for Microbiology, 2005)Iatrogenic cutaneous infection with vaccinia virus (VV) and naturally occurring systemic infection with variola virus both lead to the characteristic skin "pox" lesions. Despite significant medical experience with both ... -
Vacuum Decay Constraints on a Cosmological Scalar Field
(American Physical Society, 2002)If the potential of a scalar filed phi which currently provides the dark energy of the Universe has a minimum at phi = -M-0(4) < 0, then quantum-mechanical fluctuations could nucleate a bubble of &phi; at a negative ... -
Vacuum Instabilities with a Wrong-Sign Higgs-Gluon-Gluon Amplitude
(IOP Publishing, 2013-03-19)The recently discovered 125 GeV boson appears very similar to a Standard Model Higgs, but with data favoring an enhanced \(h \rightarrow \gamma \gamma\) rate. A number of groups have found that fits would allow (or, less ... -
Vacuum states for AdS2 black holes
(Springer Verlag, 1999)An AdS(2) black hole spacetime is an AdS(2) spacetime together with a preferred choice of time. The Boulware, Hartle-Hawking and SL(2; R) invariant vacua are constructed, together with their Green functions and stress ...