Now showing items 1-4 of 4

    • Circulating Mitochondrial DNA in Patients in the ICU as a Marker of Mortality: Derivation and Validation 

      Nakahira, Kiichi; Kyung, Sun-Young; Rogers, Angela J.; Gazourian, Lee; Youn, Sojung; Massaro, Anthony F.; Quintana, Carolina; Osorio, Juan C.; Wang, Zhaoxi; Zhao, Yang; Lawler, Laurie A.; Christie, Jason D.; Meyer, Nuala J.; Causland, Finnian R. Mc.; Waikar, Sushrut S.; Waxman, Aaron B.; Chung, Raymond T.; Bueno, Raphael; Rosas, Ivan O.; Fredenburgh, Laura E.; Baron, Rebecca M.; Christiani, David C.; Hunninghake, Gary M.; Choi, Augustine M. K. (Public Library of Science, 2013)
      Background: Mitochondrial DNA (mtDNA) is a critical activator of inflammation and the innate immune system. However, mtDNA level has not been tested for its role as a biomarker in the intensive care unit (ICU). We hypothesized ...
    • Diagnosing sepsis is subjective and highly variable: a survey of intensivists using case vignettes 

      Rhee, Chanu; Kadri, Sameer S.; Danner, Robert L.; Suffredini, Anthony F.; Massaro, Anthony F.; Kitch, Barrett T.; Lee, Grace; Klompas, Michael (BioMed Central, 2016)
      Background: Sepsis is the focus of national quality improvement programs and a recent public reporting measure from the Centers for Medicare and Medicaid Services. However, diagnosing sepsis requires interpreting nonspecific ...
    • Expired Nitric Oxide after Bronchoprovocation and Repeated Spirometry in Patients with Asthma 

      Deykin, Aaron; Halpern, Orit; Massaro, Anthony; Drazen, Jeffrey; Israel, Elliot (American Thoracic Society, 1998-03)
      Compared with normal individuals, subjects with asthma have elevated levels of expired nitric oxide (NO). These levels are hypothesized to reflect the degree of airway inflammation. Expired NO levels rise during the late ...
    • Influence of Patients' Preferences and Treatment Site on Cancer Patients' End-of-Life Care 

      Wright, Alexi Anne; Mack, Jennifer Williams; Kritek, Patricia A.; Balboni, Tracy; Massaro, Anthony Francis; Matulonis, Ursula Anne; Block, Susan Dale; Prigerson, Holly (Wiley-Blackwell, 2010)
      BACKGROUND: Research suggests that patients' end-of-life (EOL) care is determined primarily by the medical resources available, and not by patient preferences. The authors examined whether patients' desire for life-extending ...