Browsing by Author "Berretta, Sabina"
Now showing items 1-5 of 5
-
Extracellular Matrix Abnormalities in the Amygdala of Subjects with Schizophrenia
Brown, ChristopherSchizophrenia is a chronic, progressive disease distinguished by bizarre thinking, emotional disturbances, difficulties in motivation, and social dysfunction. Consistent findings have linked the GABAergic neurotransmitter ... -
In Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric Disorders
Pantazopoulos, Harry; Berretta, Sabina (Hindawi Publishing Corporation, 2016)Rapidly emerging evidence implicates perineuronal nets (PNNs) and extracellular matrix (ECM) molecules that compose or interact with PNNs, in the pathophysiology of several psychiatric disorders. Studies on schizophrenia, ... -
Losing the sugar coating: Potential impact of perineuronal net abnormalities on interneurons in schizophrenia
Berretta, Sabina; Pantazopoulos, Charalampos; Markota, Matej; Brown, Christopher; Batzianouli, Eleni T. (Elsevier BV, 2015-09)Perineuronal nets (PNNs) were shown to be markedly altered in subjects with schizophrenia. In particular, decreases of PNNs have been detected in the amygdala, entorhinal cortex and prefrontal cortex. The formation of these ... -
Postmortem neuropathology in early Huntington disease
Hedreen, John; Berretta, Sabina; White, Charles III (Oxford University Press (OUP), 2024-03-29)Two aspects of the neuropathology of early Huntington disease (HD) are examined. Neurons of the neostriatum are counted to determine relative loss in striosomes versus matrix at early stages, including for the first time ... -
Proteoglycan abnormalities in olfactory epithelium tissue from subjects diagnosed with schizophrenia
Pantazopoulos, Harry; Boyer-Boiteau, Anne; Holbrook, Eric Hans; Jang, Woochan; Hahn, Chang-Gyu; Arnold, Steven E.; Berretta, Sabina (Elsevier BV, 2013)Emerging evidence points to proteoglycans abnormalities in the pathophysiology of schizophrenia (SZ). In particular, markedly abnormal expression of chondroitin sulfate proteoglycans (CSPGs), key components of the extracellular ...