Browsing by Author "Torella, Joseph P."
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Rapid construction of insulated genetic circuits via synthetic sequence-guided isothermal assembly
Torella, Joseph P.; Boehm, Christian R.; Lienert, Florian; Chen, Jan-Hung; Way, Jeffrey C.; Silver, Pamela A. (Oxford University Press, 2013)In vitro recombination methods have enabled one-step construction of large DNA sequences from multiple parts. Although synthetic biological circuits can in principle be assembled in the same fashion, they typically contain ... -
Synthetic biology approaches to bio-based chemical production
Torella, Joseph Peter (2014-10-22)Inexpensive petroleum is the cornerstone of the modern global economy despite its huge environmental costs and its nature as a non-renewable resource. While ninety percent of petroleum is ultimately used as fuel and can ... -
Two- and three-input TALE-based AND logic computation in embryonic stem cells
Lienert, Florian; Torella, Joseph P.; Chen, Jan-Hung; Norsworthy, Michael; Richardson, Ryan R.; Silver, Pamela A. (Oxford University Press, 2013)Biological computing circuits can enhance our ability to control cellular functions and have potential applications in tissue engineering and medical treatments. Transcriptional activator-like effectors (TALEs) represent ...