Now showing items 1-2 of 2

    • Rapid construction of insulated genetic circuits via synthetic sequence-guided isothermal assembly 

      Torella, Joseph P.; Boehm, Christian R.; Lienert, Florian; Chen, Jan-Hung; Way, Jeffrey C.; Silver, Pamela A. (Oxford University Press, 2013)
      In vitro recombination methods have enabled one-step construction of large DNA sequences from multiple parts. Although synthetic biological circuits can in principle be assembled in the same fashion, they typically contain ...
    • Two- and three-input TALE-based AND logic computation in embryonic stem cells 

      Lienert, Florian; Torella, Joseph P.; Chen, Jan-Hung; Norsworthy, Michael; Richardson, Ryan R.; Silver, Pamela A. (Oxford University Press, 2013)
      Biological computing circuits can enhance our ability to control cellular functions and have potential applications in tissue engineering and medical treatments. Transcriptional activator-like effectors (TALEs) represent ...