Browsing by Author "Ha, Heather Jiwon"
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Stable, uncleaved HIV-1 envelope glycoprotein gp140 forms a tightly folded trimer with a native-like structure
Kovacs, James; Noeldeke, Erik; Ha, Heather Jiwon; Peng, Hanqin; Rits-Volloch, Sophia; Harrison, Stephen; Chen, Bing (National Academy of Sciences, 2014)The HIV-1 envelope spike [trimeric (gp160)(3), cleaved to (gp120/gp41)(3)] is the mediator of viral entry and the principal target of humoral immune response to the virus. Production of a recombinant preparation that ...