Now showing items 1-1 of 1

    • Rational Discovery of Antimetastatic Agents Targeting the Intrinsically Disordered Region of MBD2 

      Na, Insung; Alterovitz, Gil; Kim, Min Kyoung; Kim, Ji Sook; Son, Seung Han; Choi, Sungwoo; Lee, Seol Eui; Kim, Ji-Hun; Jang, Kiseok; Chen, Yu; van der Vaart, Arjan; Won, Hyung-Sik; Uversky, Vladamir; Kim, Chul Geon (American Association for the Advancement of Science (AAAS), 2019-11)
      Although intrinsically disordered protein regions (IDPRs) are commonly engaged in promiscuous protein-protein interactions (PPIs), using them as drug targets is challenging due to their extreme structural flexibility. We ...