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The Discovery and Characterization of Endosomal Escape Enhancing Compounds to Improve Protein Delivery Efficacy
Li, Margie (2015-07-23)The inefficient delivery of proteins into mammalian cells remains a major barrier to realizing the therapeutic potential of many proteins. We and others have previously shown that superpositively charged proteins are ... -
Discovery and Characterization of Novel smORF-Encoded Polypeptides (SEPs)
Ma, Jiao (2016-01-04)Peptides and small proteins have essential physiological roles including metabolism (insulin), sleep (orexin), and stress (corticotropin-releasing hormone). Recent exploration of the human genome and proteome has revealed ...