Browsing by Author "H. Fahey, Frederic"

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    • The Voltage–gated Proton Channel, Hv1, Enhances Brain Damage from Ischemic Stroke 

      Wu, Long–Jun; Wu, Gongxiong; Akhavan Sharif, M. Reza; Baker, Amanda; Jia, Yonghui; H. Fahey, Frederic; Luo, Hongbo; Feener, Edward Paul; Clapham, David Eldon (2012)
      Phagocytic cell NADPH oxidase (NOX) generates reactive oxygen species (ROS) as part of innate immunity. Unfortunately, ischemia can also induce this pathway and inflict damage on native cells. Here we show that NOX–mediated ...