Browsing by Author "Vakkasoglu, Ahmet"
Now showing items 1-2 of 2
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D-helix influences dimerization of the ATP-binding cassette (ABC) transporter associated with antigen processing 1 (TAP1) nucleotide-binding domain
Vakkasoglu, Ahmet; Srikant, Sriram; Gaudet, Rachelle (Public Library of Science (PLoS), 2017)ATP-binding cassette (ABC) transporters form a large family of transmembrane importers and exporters. Using two nucleotide-binding domains (NBDs), which form a canonical ATP-sandwich dimer at some point within the transport ... -
Mechanistic Determinants of the Directionality and Energetics of Active Export by a Heterodimeric ABC Transporter
Grossmann, Nina; Vakkasoglu, Ahmet Selim; Hulpke, Sabine; Abele, Rupert; Gaudet, Rachelle; Tampé, Robert (Nature Publishing Group, 2014)The ATP-binding cassette (ABC) transporter associated with antigen processing (TAP) participates in immune surveillance by moving proteasomal products into the endoplasmic reticulum (ER) lumen for major histocompatibility ...